Pancreatin is used for alternative treatments for pancreatic insufficiency due to exocrine function due to various causes. Pancreatin contains a variety of digestive enzymes such as trypsin and amylase, which can digest proteins, starches, and also have a digestive effect on fats. Pancreatin is used for indigestion in patients with pancreatic dysfunction and diabetes.
Pancreatin has a hydrolytic effect on fats, starches and proteins. After oral administration, the capsule dissolves in the stomach, releasing hundreds of enteric-coated pancreatic enzyme particles. Inactivation in the stomach can be avoided and well mixed with food in the stomach, entering the duodenum synchronously with food. The particles in the proximal duodenum immediately disintegrate and release more than 80% of the activity within 130min to ensure the digestion and absorption of nutrients.