Wednesday, June 18, 2025

China Manufacturer High Quality GLUCAM P-10/20 CAS 61849-72-7 Wholesale & Bulk

 China Manufacturer High Quality GLUCAM P-10/20 CAS 61849-72-7 Wholesale & Bulk

Glucam PPG-20 methyl glucose ether has the special property of reducing the viscosity of surface-active agents and of foaming effect.

 

Specifications of GLUCAM P-10/20 CAS 61849-72-7

 

Parameters of GLUCAM P-10/20 CAS 61849-72-7

 

Our packages of GLUCAM P-10/20 Cas 61849-72-7 Wholesale

 

As one of active pharmaceutical ingredient manufacturers, we will do our best to meet all the needs of customers.



China Manufacturer Polyethylene 2,5-furandicarboxylate CAS 28728-19-0 Wholesale & Bulk

 China Manufacturer Polyethylene 2,5-furandicarboxylate CAS 28728-19-0 Wholesale & Bulk

Polyethylene 2,5-furandicarboxylate (PEF) is a bio-based polyester made from 2,5-furandicarboxylic acid (FDCA) and ethylene glycol, derived from renewable resources like sugars. It serves as a sustainable alternative to petroleum-based PET. PEF excels in gas barrier properties (5–10× better than PET for O₂/CO₂), enhancing food/beverage packaging shelf life. It also offers higher thermal stability (~85°C glass transition) and mechanical strength. Applications include bottles, films, and textiles. PEF reduces carbon emissions by 50–70% and is recyclable, though high FDCA production costs and scaling challenges hinder mass adoption. Pioneered by companies like Avantium, it aligns with circular economy goals.

 

Polyethylene 2,5-Furandicarboxylate (PEF) is a bio-based polyester synthesized from renewable resources, primarily derived from 2,5-furandicarboxylic acid (FDCA) and ethylene glycol. It is considered a sustainable alternative to petroleum-based polyesters like PET (polyethylene terephthalate).

 

Key Features

Structure: Composed of FDCA (produced from sugars or biomass) and ethylene glycol.

 

Properties:

 

Superior Gas Barrier: 5–10× better oxygen (O₂) and carbon dioxide (CO₂) resistance than PET, ideal for food/beverage packaging.

 

Thermal Stability: Higher glass transition temperature (~85°C vs. PET’s 75°C).

 

Mechanical Strength: Enhanced tensile strength and durability.

 

Sustainability: Reduces carbon footprint by 50–70% compared to PET; recyclable and potentially biodegradable.

 

Applications

Food & Beverage Packaging: Bottles, containers, and films (extends shelf life).

 

High-Performance Films: Industrial packaging, barrier layers for electronics.

 

Textiles: Fibers for durable and heat-resistant fabrics.

 

Advantages Over PET

 

Commercial Status

Pioneers: Companies like Avantium (Netherlands) are scaling production for bottles and films.

 

Challenges: High FDCA production costs and need for optimized recycling infrastructure.

 

Future Outlook

PEF is poised to revolutionize sustainable packaging, textiles, and industrial materials, aligning with global circular economy goals. Its performance and eco-credentials make it a key player in reducing plastic pollution.

 

If you want to know more types of active pharmaceutical ingredients, please visit our website.

 

 



China Supplier 2-(4-Chlorophenoxy)-2-methylpropionic acid CAS 882-09-7 Wholesale & Bulk

 China Supplier 2-(4-Chlorophenoxy)-2-methylpropionic acid CAS 882-09-7 Wholesale & Bulk

2-(4-Chlorophenoxy)-2-methylpropionic Acid (C₁₀H₁₁ClO₃) is a chlorinated organic compound featuring a propionic acid backbone with a 4-chlorophenoxy group and a methyl group attached to the α-carbon. A white crystalline solid, it is sparingly water-soluble but dissolves in organic solvents. Primarily used as an intermediate in agrochemical synthesis, its structure resembles phenoxy herbicides (e.g., MCPA), suggesting potential herbicidal or plant-growth-regulating activity. It is synthesized via Williamson ether reaction between 4-chlorophenol and 2-bromo-2-methylpropionic acid. Handle with care—it may irritate skin/eyes. Environmental release risks exist due to its chlorinated aromatic moiety. Specific applications require further research validation.

 

2-(4-Chlorophenoxy)-2-methylpropionic Acid

Chemical Structure: A propionic acid derivative with a 4-chlorophenoxy group and methyl group attached to the α-carbon (second carbon of the carboxylic acid chain).

 

Key Properties:

 

Formula: C₁₀H₁₁ClO₃ | Molecular Weight: 214.65 g/mol

 

CAS No.: 882-09-7

 

Physical State: Likely a crystalline solid (exact melting point varies by purity).

 

Solubility: Limited in water; more soluble in organic solvents (e.g., ethanol, acetone).

 

Applications:

 

Agrochemicals: Structurally similar to phenoxy herbicides (e.g., MCPA or 2,4-D), suggesting potential use as a plant growth regulator or herbicide.

 

Organic Synthesis: Intermediate for pharmaceuticals or fine chemicals due to its reactive carboxylic acid and aromatic groups.

 

Synthesis: Typically via Williamson ether synthesis, reacting 4-chlorophenol with 2-bromo-2-methylpropionic acid under basic conditions.

 

Safety:

 

Hazards: Irritant (skin/eyes); handle with gloves/goggles.

 

Environmental Impact: Potential ecotoxicity if released (chlorinated aromatic structure).

 

Regulatory Status: Not widely regulated but subject to agrochemical guidelines if used commercially.

 

Note: Specific applications require verification via scientific literature or regulatory databases.

 

If you want to know more types of active pharmaceutical ingredients, please visit our website.

 



China Supplier Glyoxylic acid monohydrate CAS 563-96-2 Wholesale & Bulk

 China Supplier Glyoxylic acid monohydrate CAS 563-96-2 Wholesale & Bulk

Glyoxylic Acid Monohydrate (CAS 563-96-2) is a white, crystalline compound with the formula C₂H₂O₃·H₂O. It is the hydrated form of glyoxylic acid, an α-keto acid containing a carboxylic acid and a ketone group. Highly water-soluble and acidic, it is used in organic synthesis (e.g., pharmaceuticals like allantoin, agrochemicals, and polymers) and niche cosmetic peels for exfoliation. Its reactive keto group enables condensation and nucleophilic addition reactions. Corrosive and hygroscopic, it requires careful handling (gloves, goggles) and storage in cool, dry conditions. Though less common than glycolic acid in skincare, it serves specialized roles in formulations.

 

Glyoxylic Acid Monohydrate (CAS 563-96-2): A Detailed Overview

 

  1. Chemical Identity

IUPAC Name: Oxoacetic acid monohydrate

 

Chemical Formula: C₂H₂O₃·H₂O

 

CAS Number: 563-96-2 (monohydrate form)

 

Molecular Weight: 108.05 g/mol

 

Structure: An alpha-keto acid (keto group adjacent to carboxylic acid) with one water molecule of crystallization.

 

  1. Physical Properties

Appearance: White crystalline solid.

 

Solubility: Highly soluble in water, slightly soluble in ethanol.

 

Melting Point: ~50–52°C (monohydrate decomposes upon heating).

 

pH: Strongly acidic (pKa ~3.18 for the carboxylic acid group).

 

Hygroscopicity: Absorbs moisture from the air.

 

  1. Key Applications

Organic Synthesis

Pharmaceuticals: Precursor for drugs like allantoin (skin protectant) and vanillin (flavoring agent).

 

Agrochemicals: Used in herbicides (e.g., glyphosate intermediates) and plant growth regulators.

 

Polymers: Cross-linking agent in resins and adhesives (e.g., urea-glyoxal resins).

 

Cosmetics

Chemical Peels: Acts as a keratolytic agent, promoting exfoliation (less common than glycolic acid but used in specialized formulations).

 

Biochemistry

Enzyme Studies: Substrate or inhibitor in studies of glyoxylate cycle enzymes.

 

  1. Reactivity & Stability

Reactivity:

 

Undergoes nucleophilic addition (e.g., with amines to form Schiff bases).

 

Participates in condensation reactions (e.g., with urea to produce hydantoin).

 

Stability:

 

Sensitive to heat, light, and oxidation.

 

Store in cool, dry conditions (see storage guidelines below).

 

  1. Safety & Handling

Hazards:

 

Corrosive: Causes skin/eye irritation (wear gloves, goggles).

 

Inhalation Risk: Dust may irritate respiratory tract.

 

Environmental Impact: Biodegradable but toxic to aquatic life at high concentrations.

 

Regulatory Status:

 

Listed under EU REACH regulations.

 

Cosmetic use is restricted (check local guidelines for concentration limits).

 

  1. Comparison to Similar Compounds

 

  1. Storage Recommendations

Store in airtight containers away from light and moisture.

 

Ideal temperature: 2–8°C (refrigeration recommended for long-term stability).

 

  1. Industrial Suppliers

Commonly available from chemical suppliers like:

 

Sigma-Aldrich

 

TCI Chemicals

 

Alfa Aesar

 

Conclusion

Glyoxylic acid monohydrate is a versatile, reactive compound with broad applications in organic synthesis, agrochemicals, and niche cosmetic formulations. Its strong acidity and hygroscopic nature require careful handling, but its role as a precursor in pharmaceuticals and polymers makes it industrially valuable. Always verify regulatory compliance for specific uses.

 

Now the price of chemistry for sale is reasonable, anything you need, please contact us.

 

 

 



China Supplier Top quality Glyoxylic Acid CAS 298-12-4 Wholesale & Bulk

 China Supplier Top quality Glyoxylic Acid CAS 298-12-4 Wholesale & Bulk

Introduction of Glyoxylic acid.

 

Glyoxylic acid is an organic compound with the chemical formula C₂H₂O₃. It is a colorless solid that is highly soluble in water and exists in various forms, including its monohydrate and anhydrous forms. Structurally, glyoxylic acid is the simplest α-keto acid, containing both a carboxyl group (-COOH) and a keto group (C=O) attached to the same carbon atom.

 

Here are some key points about glyoxylic acid:

 

Chemical Structure: The molecular structure of glyoxylic acid can be represented as HC(O)COOH. It is the simplest member of the α-keto acids, which are characterized by having a keto group adjacent to a carboxyl group.

 

Physical Properties: Glyoxylic acid is typically found as a colorless crystalline solid or as a solution in water. It is highly soluble in water and can form hydrates.

 

Introduction of Glyoxylic acid.

 

Glyoxylic acid is an organic compound with the chemical formula C₂H₂O₃. It is a colorless solid that is highly soluble in water and exists in various forms, including its monohydrate and anhydrous forms. Structurally, glyoxylic acid is the simplest α-keto acid, containing both a carboxyl group (-COOH) and a keto group (C=O) attached to the same carbon atom.

 

Here are some key points about glyoxylic acid:

 

Chemical Structure: The molecular structure of glyoxylic acid can be represented as HC(O)COOH. It is the simplest member of the α-keto acids, which are characterized by having a keto group adjacent to a carboxyl group.

 

Physical Properties: Glyoxylic acid is typically found as a colorless crystalline solid or as a solution in water. It is highly soluble in water and can form hydrates.

 

Chemical Properties: Glyoxylic acid is a reactive compound due to the presence of both the carboxyl and keto functional groups. It can participate in various chemical reactions, including oxidation, reduction, and condensation reactions.

 

Natural Occurrence: Glyoxylic acid is an intermediate in various metabolic pathways in living organisms, including the glyoxylate cycle, which is a variation of the citric acid cycle.

 

Synthesis: Industrially, glyoxylic acid can be synthesized through the oxidation of glyoxal or by the hydrolysis of oxalic acid esters.

 

Application of Glyoxylic acid.

 

Glyoxylic acid has a variety of applications across different industries due to its reactive nature and functional groups. Here are some of its key applications:

 

Cosmetics and Personal Care: Glyoxylic acid is used in hair care products, particularly in hair straightening and smoothing treatments. It helps to alter the hair’s structure, making it easier to manage and style.

 

Pharmaceuticals: It serves as an intermediate in the synthesis of various pharmaceutical compounds. Glyoxylic acid is involved in the production of certain drugs and active pharmaceutical ingredients (APIs).

 

Chemical Synthesis: Glyoxylic acid is a valuable intermediate in organic synthesis. It is used to produce a range of chemicals, including vanillin (a flavoring agent), allantoin (a skin conditioning agent), and other fine chemicals.

 

Agriculture: In the agricultural sector, glyoxylic acid is used in the synthesis of herbicides and plant growth regulators. It helps in the production of compounds that control plant growth and protect crops from pests.

 

Food Industry: Glyoxylic acid is used as a flavoring agent and preservative in the food industry. It can be involved in the synthesis of flavor compounds and other food additives.

 

Textile Industry: It is used in the textile industry for fabric finishing processes. Glyoxylic acid can help improve the texture and appearance of fabrics.

 

Water Treatment: Glyoxylic acid is used in water treatment processes to remove impurities and contaminants. It can act as a chelating agent, binding to metal ions and facilitating their removal from water.

 

Polymer Industry: It is used in the production of certain polymers and resins. Glyoxylic acid can be a building block for creating polymeric materials with specific properties.

 

These applications highlight the versatility of glyoxylic acid in various industrial and commercial sectors. Its reactivity and functional groups make it a valuable compound for a wide range of chemical processes and products.

 

FAQ From Wuhan Fortuna Chemical Co.,Ltd

Q

Can I get a sample for free ?

A

For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.

 

Q

How to confirm the product quality before placing orders ?

A

Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.

 

Q

What is the payment you accept?

A

For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.

 

Q

What is your shipment way ?

A

For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.

 

Q

How long is your after-sales service?

A

We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.

 

Q

How do you treat quality complaint ?

 

A

We support customer to provide our products to any rightful   third party testing organization to test our products according to the COA   specification, if the test result is confirm with COA, we will take all the   loss for customers.

 

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is  the members of Hubei E-commerce Chamber.

 

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.

 

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.

 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.

 

Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Glyoxylic acid with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Glyoxylic acid.

 

Packing of Glyoxylic Acid CAS 298-12-4 Wholesale

 

Unique Advantages For Glyoxylic Acid CAS 298-12-4 Bulk

Guaranteed the purity

High quality & competitive price

Quality control

Fast feedback

Prompt shipment

 

If you want to know more types of chemical product, please visit our website.

 

 



China Supplier Ascorbyl glucoside CAS 129499-78-1 Wholesale & Bulk

 China Supplier Ascorbyl glucoside CAS 129499-78-1 Wholesale & Bulk

Ascorbic acid 2-O-glucoside (AA2G) is a stabilized derivative of vitamin C (ascorbic acid) where a glucose molecule is attached via an ether bond to the hydroxyl group on the 2nd carbon of ascorbic acid. This glycosylation protects the antioxidant from oxidation, enhancing its stability against light, heat, and air compared to pure ascorbic acid. Widely used in cosmetics and skincare, it slowly releases vitamin C upon enzymatic breakdown, providing prolonged antioxidant effects, brightening skin, and boosting collagen synthesis. It is also used in food and pharmaceuticals as a non-irritating, water-soluble vitamin C source. Synthesized via enzymatic or chemical glycosylation, AA2G combines vitamin C’s benefits with improved shelf life and bioavailability.

 

Ascorbyl Glucoside: A Comprehensive Overview

 

  1. Chemical Structure and Composition:

 

Ascorbyl Glucoside is a stable, water-soluble derivative of Vitamin C (ascorbic acid) where a glucose molecule is bonded to ascorbic acid. This glycosidic bond enhances stability and solubility.

 

  1. Stability and Solubility:

 

Unlike pure L-ascorbic acid, which is prone to oxidation, Ascorbyl Glucoside is more stable in formulations, especially in water-based products, due to its hydrophilic glucose moiety. It does not degrade rapidly when exposed to air or light.

 

  1. Mechanism of Action:

 

Upon application, skin enzymes (e.g., α-glucosidase) hydrolyze the glucoside bond, releasing active Vitamin C gradually. This controlled release ensures sustained antioxidant activity and minimizes irritation.

 

  1. Skincare Benefits:

 

Antioxidant Protection: Neutralizes free radicals from UV exposure and pollution.

 

Collagen Synthesis: Stimulates collagen production, reducing wrinkles and improving elasticity.

 

Brightening Effect: Inhibits tyrosinase, reducing melanin synthesis to address hyperpigmentation and uneven skin tone.

 

Gentle Formulation: Suitable for sensitive skin due to its mild nature and slow conversion process.

 

  1. Efficacy and Clinical Support:

 

Studies indicate effectiveness in improving skin texture, brightness, and reducing photodamage. For example, a 2012 study in International Journal of Cosmetic Science showed significant improvement in skin tone and hydration with 2% Ascorbyl Glucoside.

 

  1. Comparison to Other Vitamin C Derivatives:

 

Sodium Ascorbyl Phosphate (SAP): More stable than L-ascorbic acid but less potent in collagen synthesis.

 

Magnesium Ascorbyl Phosphate (MAP): Oil-soluble, ideal for moisturizers; moderate efficacy.

 

Ethylated Ascorbic Acid: Highly stable and lipid-soluble, with deep penetration.

 

  1. Formulation and Usage:

 

Commonly found in serums, moisturizers, and sunscreens at concentrations of 0.5–2%. Often paired with other antioxidants (e.g., Vitamin E) or brightening agents (e.g., niacinamide) for synergistic effects.

 

  1. Safety and Regulatory Status:

 

Generally recognized as safe by the Cosmetic Ingredient Review (CIR). Rarely causes irritation, making it suitable for long-term use across skin types.

 

  1. Storage Considerations:

 

While more stable than pure Vitamin C, products are still best stored in opaque, airtight containers to prolong shelf life, though less stringent than L-ascorbic acid requirements.

 

  1. Brand Examples:

 

Featured in products from The Ordinary, Paula’s Choice, and NIOD, often marketed for brightening and anti-aging benefits.

 

Conclusion: Ascorbyl Glucoside is a versatile, stable Vitamin C derivative ideal for those seeking gentle yet effective antioxidant and anti-aging benefits without the instability of pure ascorbic acid. Its gradual conversion ensures sustained efficacy, making it a popular choice in cosmetic formulations.

 

If you want to know more types of chemical industry products, please visit our website.

 

 



China Suppliers SORBITAN CAPRYLATE High quality with good service Wholesale & Bulk

 China Suppliers SORBITAN CAPRYLATE High quality with good service Wholesale & Bulk

Sorbitan Caprylate is a nonionic surfactant and emulsifier synthesized from sorbitol (a sugar alcohol) and caprylic acid (C8 fatty acid). It stabilizes oil-water mixtures, making it vital in cosmetics (creams, lotions), pharmaceuticals (ointments), and food (as an additive, e.g., E494). Its dual hydrophilic-lipophilic properties (HLB ~4-6) enable use in both oil-in-water and water-in-oil systems. Mild and biodegradable, it enhances product texture, prevents separation, and solubilizes oils/fragrances. Regulated as safe by FDA (21 CFR) and EU cosmetics standards, it is low-irritation, suitable for sensitive skin, and found in moisturizers, sunscreens, and processed foods like baked goods.

 

Sorbitan Caprylate is a nonionic surfactant and emulsifier derived from sorbitol (a sugar alcohol) and caprylic acid (a medium-chain fatty acid, C8). It is widely used in cosmetics, pharmaceuticals, and food products due to its ability to stabilize mixtures of oil and water. Here’s a detailed breakdown:

 

  1. Chemical Structure

Formed by esterifying sorbitol with caprylic acid (octanoic acid), resulting in a molecule with both hydrophilic (water-attracting) and lipophilic (oil-attracting) properties.

 

Chemical formula: Typically represented as C14H26O6 (varies slightly based on esterification degree).

 

  1. Key Functions

Emulsifier: Stabilizes oil-in-water (O/W) or water-in-oil (W/O) emulsions, preventing separation.

 

Solubilizer: Helps dissolve oils, fragrances, or hydrophobic actives in water-based formulations.

 

Texture Enhancer: Improves the spreadability and smoothness of creams, lotions, and cosmetic products.

 

  1. Applications

Cosmetics & Personal Care

Skincare: Used in creams, lotions, sunscreens, and serums for even texture and stability.

 

Haircare: Found in conditioners or styling products to enhance softness and manageability.

 

Makeup: Stabilizes foundations, lipsticks, and mascaras.

 

Pharmaceuticals

Topical ointments, creams, or gels to uniformly disperse active ingredients.

 

Food Industry (regulated use)

Approved as a food additive (E494 in some regions) for emulsifying baked goods, confectionery, or processed foods.

 

Industrial Uses

Lubricants, coatings, or agrochemical formulations.

 

  1. Safety & Regulation

Safety: Generally recognized as safe (GRAS) for topical and limited food use. Non-irritating and suitable for sensitive skin.

 

Regulatory Status:

 

Approved by the FDA (21 CFR) for food and cosmetic use.

 

Listed in the EU Cosmetics Regulation (INCI name: Sorbitan Caprylate).

 

Complies with ISO, USP, and other pharmacopeial standards.

 

  1. Advantages

Mild and biodegradable.

 

Enhances product stability without compromising sensory qualities (e.g., lightweight feel).

 

  1. Example Products

Moisturizers, sunscreen lotions, medicated creams, and processed foods like whipped toppings.

 

In summary, Sorbitan Caprylate is a versatile, safe ingredient that improves texture and stability in formulations across industries. Always check local regulations for specific usage limits.

 

As one of chemical wholesale suppliers, we will do our best to meet all the needs of customers.

 

 



China Manufacturer Ivabradine Hydrochloride CAS 148849-67-6 Wholesale & Bulk

 China Manufacturer Ivabradine Hydrochloride CAS 148849-67-6 Wholesale & Bulk

Ivabradine hydrochloride is a selective and specific heart rate regulating inhibitor.

 

 

Our Packages of Product CAS 148849-67-6 :10g,100g,1kg/foil bag Wholesale

 

Unique Advantages For Ivabradine Hydrochloride CAS 148849-67-6 Bulk

Guaranteed purity

High quality & competitive price

Quality control

Fast feedback

Prompt shipment

 

If you want to know more types of laboratory chemicals, please visit our website.

 

 



China Manufacturer supply Azilsartan Impurity 16 CAS 1417576-00-1 Wholesale & Bulk

 China Manufacturer supply Azilsartan Impurity 16 CAS 1417576-00-1 Wholesale & Bulk

Azilsartan Impurity 16 is a specified degradation product or synthetic byproduct identified during the manufacturing or storage of Azilsartan medoxomil, an angiotensin II receptor blocker (ARB) used to treat hypertension. It is structurally related to the active pharmaceutical ingredient (API) but differs due to unintended chemical modifications during synthesis or decomposition. Regulatory bodies like the ICH mandate strict control of such impurities to ensure drug safety and efficacy. While its exact structure may vary, it typically arises from incomplete reactions, isomerization, or oxidation of intermediates. Analytical methods (e.g., HPLC, LC-MS) are used to quantify it, adhering to limits set by pharmacopeial standards (e.g., USP, EP). Proper identification is critical for quality control.

 

Azilsartan Impurity 16 is a identified byproduct or degradation product associated with the synthesis or storage of Azilsartan medoxomil, an angiotensin II receptor blocker (ARB) used to treat hypertension. Here's a structured summary:

 

Origin:

 

Likely arises during the synthesis of Azilsartan medoxomil (e.g., incomplete reactions, side reactions, or intermediates) or from degradation (e.g., hydrolysis, oxidation, or exposure to light/heat).

 

Structural Characteristics:

 

While the exact structure isn't specified here, impurities in ARBs like Azilsartan often relate to modifications in the tetrazole ring, ester group (medoxomil moiety), or substituents. It could be a positional isomer, dimer, or derivative with altered functional groups.

 

Regulatory Context:

 

Governed by ICH guidelines, impurities must be identified, quantified, and controlled if they exceed thresholds (typically ≥0.1% of the drug substance). Regulatory filings (e.g., FDA NDA, EMA reports) detail such impurities to ensure safety.

 

Analytical Control:

 

Characterized using techniques like HPLC, LC-MS, or NMR. Manufacturers monitor its levels to comply with pharmacopeial standards (USP, Ph. Eur.) and ensure it remains within safe limits.

 

Significance:

 

Critical for drug quality and patient safety. Even non-toxic impurities must be controlled to avoid batch variability or stability issues.

 

For the precise structure or toxicological profile, consulting Azilsartan’s drug master file, FDA/EMA assessment reports, or peer-reviewed studies would be necessary. These sources often provide chemical names, structural diagrams, and synthesis pathways for listed impurities.

 

If you want to know more types of fine chemicals, please visit our website.

 

 

 



Wednesday, May 28, 2025

Cypermethrin CAS 52315-07-8 Wholesale & Bulk

 Cypermethrin CAS 52315-07-8 Wholesale & Bulk

Cypermethrin is a moderately toxic pesticide that acts on the nervous system of insects and disrupts the neural function of insects by interacting with sodium channels. Cypermethrin has the characteristics of a wide insecticidal spectrum, rapid efficacy, and stability to light and heat

 

Cypermethrin is a safe and effective broad-spectrum insecticide with strong anti-killing, gastric toxicity and food inhibition effects, especially for lepidopteran pests. It is suitable for pest control on cotton, rice, vegetables, fruit trees and tea and other crops. However, it should not be used as a soil pesticide.

 

For more information about chemical product, please feel free to contact us!