key words: fluralaner,CAS NO 864731-61-3,fluralaner specification
Fluralaner is a potent acaricide and insecticide from the isoxazoline drug class.
Fluralaner works mainly by interfering with GABA-gated chloride channels, similar to the targets of insecticides such as cyclopentadienes, phenylpyrazoles and macrolides.
Fluralaner is a broad-spectrum pesticide with good insecticidal activity against pests such as ticks, fleas, lice, hemiptera, and diptera. It is more virulent than or comparable to commonly used pesticides.
Items | Specifications | Results |
Appearance | White to light yellow powder | Conforms |
Solubility | Freely soluble in ethyl acetate or DMF. | 0.79% |
Identification | The retention time of the major peak of the sample solution corresponds to that of the standard solution,as obtained in the Assay. | Conforms |
Water | Not more than 1.0% | Conforms |
Organic impurities | Individual unspecified impurity not more than 0.20% | Conforms |
Total impurities not more than 1.0% | Conforms | |
Residual solvent | Dichloromethane not more than 0.060% | 0.0078% |
N-hexane not more than 0.029% | 0.0052% | |
Ethyl acetate not more than 0.50% | 0.012% | |
Tetrahydrofuran not more than 0.072 % | Not detected | |
Triethylamine not more than 0.50% | Not detected | |
Toluene not more than 0.089% | 0.012% | |
DMF not more than 0.088 % | Not detected | |
Residue on ignition | Not more than 0.20% | 0.00068% |
Heavy metal | Not more than 20ppm | Not detected |
Assay | NLT 98.0% and NMT 102.0% of C22H17Cl2F6N3O3,calculated on the anhydrous basis. | 100.8% |
Conclusion | The product conforms to above standard. | |
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