China Supplier High Quality Best Price Ivermectin CAS 70288-86-7 Wholesale & Bulk
Ivermectin is a new type of high-efficiency semi-synthetic antibiotic insecticide, acaricide, nematicide, belongs to insect nerve agent, biological penetrant. The mechanism of action is to interfere with the neurophysiological activities of pests, stimulate the release of γ-aminobutyric acid, act on the nerve-muscle junction, increase the release of chloride ions, inhibit the information transmission of the nerve junction, and lead to paralysis and poisoning death of pests and pest mites. Ivermectin is a new broad-spectrum, high-efficiency, low-toxicity antiparasitic drug, which has a good repellent effect on in vivo and in vitro parasites, especially nematodes and arthropods. However, it is not effective against tapeworms, flukes, and protozoa.
Ivermectin is a good drug for the treatment of mite disease.
Primary Uses and How It Works
Function: It works by paralyzing and killing parasites. It targets the nervous system of invertebrates (like parasites) with minimal effect on humans, making it very safe for its intended uses.
Veterinary Medicine: It is extensively used to prevent and treat heartworm and other parasitic infections in animals (e.g., dogs, horses, livestock).
Human Medicine: In humans, it is FDA-approved at specific doses to treat:
Strongyloidiasis: An intestinal infection caused by the roundworm Strongyloides stercoralis.
Onchocerciasis (River Blindness): An infection caused by the parasitic worm Onchocerca volvulus, which is transmitted by blackflies.
Other Parasites: It is also used for scabies and lice.
It is on the World Health Organization's (WHO) List of Essential Medicines.
The COVID-19 Controversy
During the COVID-19 pandemic, ivermectin gained significant and controversial attention.
Early Hope: Some early laboratory studies in vitro (in a petri dish) suggested it could inhibit the SARS-CoV-2 virus. However, the concentrations required for this effect were far higher than safe and achievable levels in the human body.
Lack of Evidence: Subsequent large-scale, robust clinical trials and major health organizations (including the FDA, WHO, and CDC) found no conclusive evidence that ivermectin is effective for preventing or treating COVID-19.
Dangers of Misuse: This led to warnings against using veterinary formulations or unprescribed human doses, which can be highly toxic and cause serious harm, including nausea, vomiting, seizures, and even death.
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