1. Introduction
Sodium Hyaluronate (CAS 9067-32-7) is the sodium salt form of hyaluronic acid, widely used in cosmetic and personal care formulations for its exceptional water-binding capacity and biocompatibility. As a naturally occurring polysaccharide present in human connective tissues, it plays a fundamental role in maintaining skin hydration, elasticity, and barrier integrity.
In modern formulation science, Sodium Hyaluronate is not treated as a single-function moisturizer. Its performance is highly dependent on molecular weight distribution, concentration level, and formulation system compatibility. Understanding these parameters is essential for achieving targeted product claims and stable manufacturing outcomes.
2. Molecular Weight Classification and Functional Mechanism
The functional behavior of Sodium Hyaluronate varies significantly across molecular weight ranges. Each grade is designed to deliver specific performance attributes within cosmetic systems.
High Molecular Weight (HMW)
(typically >1,000 kDa)
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Forms a breathable, viscoelastic film on the skin surface
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Reduces transepidermal water loss (TEWL)
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Provides immediate smoothing and surface hydration
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Enhances sensory perception in creams and lotions
HMW grades are primarily used in moisturizing creams, masks, and barrier-repair formulations where surface protection is required.
Medium Molecular Weight (MMW)
(typically 300–1,000 kDa)
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Balances surface hydration and skin feel
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Improves formulation texture and spreadability
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Contributes to moderate viscosity adjustment
MMW Sodium Hyaluronate is suitable for emulsions, daily skincare products, and multifunctional hydration systems.
Low Molecular Weight (LMW)
(typically 10–300 kDa)
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Smaller molecular size enables enhanced skin penetration
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Supports long-lasting hydration and elasticity improvement
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Often positioned in anti-aging and serum-based products
LMW grades are commonly selected for advanced skincare formulations targeting deeper hydration performance.
Oligo / Ultra-Low Molecular Weight
(typically <10 kDa)
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Designed for high-performance and premium product concepts
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Used in intensive repair or high-efficacy hydration claims
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Frequently combined with higher molecular weight grades for synergistic effects
3. Concentration and Formulation Considerations
The concentration of Sodium Hyaluronate significantly influences viscosity, film formation, and sensory characteristics.
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0.05%–0.1% → Lightweight hydration, suitable for toners and light emulsions
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0.1%–0.3% → Standard moisturizing systems in creams and serums
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Above 0.3% → Intensive hydration or functional repair positioning
Formulators must also consider:
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pH stability (optimal performance typically between pH 5.0–8.0)
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Compatibility with electrolytes and active ingredients
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Hydration time and dispersion method
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Microbiological control in aqueous systems
4. Quality Control and Regulatory Compliance
Given its widespread application in global cosmetic markets, Sodium Hyaluronate must meet stringent quality standards.
Key quality parameters include:
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Controlled molecular weight distribution
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Defined viscosity range
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Purity and residual solvent control
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Microbial limits compliant with cosmetic regulations
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Documentation support (COA, MSDS, technical data sheets)
Ensuring batch-to-batch consistency is critical for large-scale cosmetic manufacturing, especially for brands operating across multiple regulatory jurisdictions.
5. Our Supply Capabilities
At [Your Company Name], we provide cosmetic-grade Sodium Hyaluronate with controlled molecular weight specifications to meet diverse formulation requirements.
Our advantages include:
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Multiple molecular weight options
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Stable and traceable raw material sourcing
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Strict quality management and batch consistency
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Technical documentation aligned with international cosmetic standards
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Reliable global supply capability
We work closely with formulators and manufacturers to support both new product development and formulation optimization, ensuring performance reliability and regulatory readiness.
6. Conclusion
Sodium Hyaluronate is not a one-dimensional moisturizing agent. Its performance is defined by molecular structure, concentration, and system compatibility. Selecting the appropriate grade is essential for achieving desired sensory characteristics, hydration depth, and product positioning.
Through controlled specifications and stable supply, we aim to support cosmetic manufacturers in delivering scientifically grounded and market-ready skincare solutions.
For detailed technical specifications or cooperation inquiries, please contact our team.
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